The Mountain Road will temporarily close tomorrow.
The section between the Creg-ny-Baa and Ramsey Hairpin is due to shut between 9.30am and 4.30pm.
It's while officials set up the one-way system in the area in preparation for the first TT practice session, which is due take place on Saturday.
Following re-opening the one-way system on the stretch will be in force throughout the racing fortnight and cycling will also be prohibited.
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Section of TT course to shut for this weekend