Police say a pedestrian has died after an incident in Onchan in the early hours of this morning.
Officers say it happened at around 3.30am on Whitebridge Road.
An investigation has been launched after one person later died in Noble's Hospital.
Whitebridge Road has now reopened after being closed since the incident.
Police are urging the public to refrain from public judgement or assumption and respect the family and friends of the person who died.