Part of the Mountain Road will be closed for much of Thursday while emergency work takes place.
The Department of Infrastructure says the section is due to remain shut until around 3.30pm.
It says its contractors need to carry out work on trees near the Waterworks.
As a result, the route will be shut between Barrule Park in Ramsey and the Bungalow.
Record-breaking heat last month, says Met Office
Complaints over Ben-My-Chree's refurb works
Census officers to visit homes of people who haven't submitted
Seagull terror forces cafe to remove outdoor seating
Not practical to give details on police call-outs, says minister
Steam Packet asks travellers to be patient
Plans for new veterinary practice submitted
We'll go to police if vandals return, says nursery