The Department of Infrastructure says a main road in Onchan will shut tomorrow morning.
King Edward Road will close between Port Jack and Main Road in Baldrine.
The DOI says a dangerous tree overhanging the road needs to be removed before it falls.
Workers from the Department of Environment, Food and Agriculture will close the route from 9.30am until 1.30pm.
Manxman sailings in doubt from tomorrow
Car falls down steep bank on Mountain Road
Panic over - Mcdonald's reopens at 11am tomorrow
Police say beat it to cars illegally parked during MJ tribute act
No dedicated prostate cancer screening programme, despite over 1,200 referrals
Minister says GP waiting times have improved, but delays still impact A&E
Crash closes section of the Mountain Road
Island's prison nears full capacity